The universe is impersonal. Things happen in it, without regard for what you want, how you want it, or the power of your personal thoughts. The universe is impersonal. It doesn't give a rat's ass whether you are happy or sad, whether your plans are disrupted, whether what comes your way is fair or just. The universe is impersonal. There is an order to it, a balance, a completeness. But none of this is taken to an individual human level. Said another way, bad things happen to good people, and good things happen to bad people. This may piss you off. This may make you cry. This may make you rail against the heavens, gnash your teeth in despair. But it is what it is. The universe is a thing of beauty, a system of infinite possibility and potential. It is also horrible and powerful and terrible, depending on where you stand while it does its magic. You are every bit as important in the whole as a bird, or a gnat, or a grain of sand, or a tree. Humanity does not make you privileged. It doesn't make you favored. It just makes you self-aware. This doesn't mean what you do or say does not matter. It does matter -- to you. To the people around you. The universe is impersonal, but you are not. Because the meaning of life IS personal, and you decide what that meaning may be.
I find great comfort, when things are not going my way, to remember this -- the universe is not personal.